Mangiameli has worked at Legal Aid of Nebraska from 1997-2003 and 2006 to present. Prior to working at Legal Aid, Mangiameli was in private practice. Mangiameli currently practices in the areas of Social Security Disability, Medicaid/Medicare and end-of-life planning. Her focus is on a holistic approach to medical care, which improves client health by removing barriers to medical care and preventing poverty.
She was appointed to the Advisory Council on Public Guardian by the State Court Administrator for the State of Nebraska and serves as vice-chair to the Council. She also serves on the Nebraska Families Collaborative Advisory Board. Mangiameli graduated Magna Cum Laude from Northern State University with a B.S. in Business Marketing/Management and is a 1991 graduate of Creighton University School of Law.